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Treatment response was measured using the

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Visual Analogue Scale (VAS), rest and mobilization, Hospital Anxiety and Depression Scale (HAD) and Eastern Cooperative Oncology Group (ECOG) and an adverse event sheet to

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record adverse events occurring during the study. On

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severe pain secondary to acute renal colic (ARC) was studied in 45 consecutive patients.

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This produced a gradual reduction of the VAS scores at rest (significant

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reduction of 5.2 /- 1.1 to 2.7

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/- 1.5 points; (p. A series of 50 casesINTRODUCTION. Six month, observational, open study, carried out in two pain units. LAS might

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therefore be applied as a first-hand

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alternative to narcotics for the treatment of ARC. The objective

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of this study is to investigate analgesic effectiveness and safety of Venlafaxine ( Effexor ) extended release in chronic pain of any etiology.

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Pain relief occurred within five minutes

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in one third of the patients while in the rest within 30 minutes. Initially, a daily dose

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of 75 mg of Venlafaxine (

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Effexor ) extended release was administered, increasing it to 150 mg, following clinical criteria. Clinically acceptable analgesia was obtained in 65% of the cases. Significant reduction of systolic blood pressure

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(mean /- S.D.) 23.8 /- 19.5, pulse rate (mean /- S.D.) 19.5 /- 10.1 and vomiting were noted in patients who had pain relief. Lysine acetyl salicylic

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acid in acute renal pain.The effect of repeated doses of 1.8 g lysine acetyl salicylic acid (LAS) i.v. No other side effects were observed. Venlafaxine ( Effexor ) extended release for the treatment of chronic pain.

No additional pain relief was achieved with the combination of pethidine 100 mg

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i.v. The incidence of nausea has increased after LAS administration. The study was carried out in a 50 patient sample with a mean age of 57.1 /- 1.8 years, with chronic pain.

A total of 85-90 % of the patients was maintained with a daily dose of 75 mg of Venlafaxine ( Effexor ) extended release.

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